Compassionate Allowance List for Social Security Disability

Compassionate Allowance list for Social Security disability

The Social Security Administration (SSA) has a program in place to help those with dire need medical issues secure the benefits they need in a timely manner. This program, the CAL initiative, consists only of conditions that automatically meet the SSA’s definition of disability.



Compassionate Allowance List for Social Security Disability Conditions

Periodically, the SSA will add new medical conditions to its compassionate allowance list for Social Security disability applicants. According to the SSA, these conditions are determined using information from public outreach hearings, comments from the Social Security and Disability Determination Services communities, counsel of medical and scientific experts, and research with the National Institutes of Health (NIH).

Here are some medical conditions currently on the compassionate allowance list for Social Security disability:

  • Acute leukemia
  • Adrenal cancer
  • Adult non-Hodgkin lymphoma
  • Late-onset Huntington’s disease
  • Aicardi-Goutieres syndrome
  • Alexander disease (ALX) – neonatal and infantile
  • Allan-Herndon-Dudley syndrome
  • Alobar holoprosencephaly
  • Alpers disease
  • Alpha-mannosidosis (type II and III)
  • Alström syndrome
  • Alveolar soft part sarcoma (ASPS)
  • Amegakaryocytic Thrombocytopenia
  • Amyotrophic Lateral Sclerosis (ALS)
  • Anaplastic adrenal cancer (with distant metastases or which are inoperable, unresectable or recurrent)
  • Angelman syndrome
  • Aortic atresia
  • Aplastic anemia
  • Astrocytoma (grade III and IV)
  • Ataxia-telangiectasia
  • Batten disease
  • Beta thalassemia major
  • Bilateral optic atrophy (infantile)
  • Bilateral retinoblastoma
  • Bladder cancer
  • Breast cancer
  • Canavan Disease (CD)
  • Carcinoma of unknown primary site
  • Cardiac amyloidosis (AL type)
  • Caudal regression syndrome (types III and IV)
  • Cerebro-oculo-facio-skeletal (COFS) syndrome
  • Cerebrotendinous xanthomatosis
  • Child lymphoblastic lymphoma
  • Child lymphoma
  • Child neuroblastoma
  • Chondrosarcoma
  • Chronic myelogenous leukemia (CML) – blast phase
  • Congenital lymphedema
  • Cornelia de Lange syndrome
  • Corticobasal degeneration
  • Creutzfeldt-Jakob disease (CJD) – adult
  • Cri-du-chat syndrome
  • Degos disease (systemic)
  • DeSanctis-Cacchione syndrome
  • Dravet syndrome
  • Early-onset Alzheimer’s disease
  • Edwards syndrome (trisomy 18)
  • Eisenmenger syndrome
  • Endometrial stromal sarcoma
  • Endomyocardial fibrosis
  • Ependymoblastoma (child brain cancer)
  • Erdheim-Chester disease
  • Esophageal cancer
  • Ewing sarcoma
  • Farber’s disease (FD) – infantile
  • Fatal familial insomnia
  • Fibrodysplasia ossificans progressiva
  • Follicular dendritic cell sarcoma (metastatic or recurrent)
  • Friedreich’s ataxia (FRDA)
  • Frontotemporal dementia (FTD), Pick’s disease – type A – adult 
  • Fryns syndrome
  • Fucosidosis (type 1)
  • Fukuyama congenital muscular dystrophy
  • Fulminant giant cell myocarditis
  • Galactosialidosis – early and late infantile types
  • Gallbladder cancer
  • Gaucher disease (GD) – type 2
  • Glioblastoma multiforme (brain cancer)
  • Glioma (grade III and IV)
  • Glutaric acidemia (type II)
  • Head and neck cancers (with distant metastases or which are either inoperable or unresectable)
  • Heart transplant graft failure
  • Heart transplant wait list (1A/1B)
  • Hemophagocytic lymphohistiocytosis (HLH) – familial type
  • Hepatoblastoma
  • Hepatopulmonary syndrome
  • Hepatorenal syndrome
  • Histiocytosis
  • Hutchinson-Gilford progeria syndrome
  • Hydranencephaly
  • Hypocomplementemic urticarial vasculitis
  • Hypophosphatasia (perinatal/lethal and infantile onset types)
  • Hypoplastic left heart syndrome
  • I-cell disease
  • Idiopathic pulmonary fibrosis
  • Infantile free sialic acid storage disease
  • Infantile neuroaxonal dystrophy (INAD)
  • Infantile neuronal ceroid lipofuscinoses
  • Inflammatory breast cancer (IBC)
  • Jervell and Lange-Nielsen syndrome
  • Junctional epidermolysis bullosa (lethal type)
  • Juvenile Huntington’s disease
  • Kidney cancer (if it’s inoperable or unresectable)
  • Krabbe disease (KD) – infantile
  • Kufs disease (Type A and B)
  • Large intestine cancer (with distant metastases or which is inoperable, unresectable or recurrent in nature)
  • Late infantile neuronal ceroid lipofuscinoses
  • Leigh syndrome
  • Leiomyosarcoma
  • Lesch-Nyhan syndrome (LNS)
  • Lewy body dementia (LBD)
  • Lissencephaly
  • Liver cancer
  • Lowe syndrome (Oculocerebrorenal syndrome)
  • Lymphomatoid granulomatosis (grade III)
  • Malignant brain stem gliomas (childhood)
  • Malignant gastrointestinal stromal tumor
  • Malignant melanoma (with metastases)
  • Malignant multiple sclerosis
  • Mantle cell lymphoma (MCL)
  • Maple syrup urine disease
  • Mastocytosis (type IV)
  • MECP2 duplication syndrome
  • Medulloblastoma
  • Menkes disease (classic or infantile onset forms)
  • Merkel cell carcinoma (with metastases)
  • Merosin-deficient congenital muscular dystrophy (MDC1A)
  • Metachromatic leukodystrophy (MLD or Arylsufatase A deficiency) – late infantile
  • Mitral valve atresia
  • Mixed dementias
  • MPS I (Hurler syndrome)
  • MPS II (Hunter syndrome)
  • MPS III (Sanfilippo syndrome)
  • Mucosal malignant melanoma
  • Multicentric Castleman’s disease
  • Multiple system atrophy
  • MERFF syndrome (myoclonic epilepsy with ragged red fibers syndrome)
  • Neonatal adrenoleukodystrophy
  • Nephrogenic systemic fibrosis
  • Neurodegeneration with brain iron accumulation (types 1 and 2)
  • NFU1 mitochondrial disease
  • Niemann-Pick Disease (NPD) – types A and C
  • Nonketotic hyperglycinemia
  • Non-small cell lung cancer (with metastases to or beyond the hilar nodes or which is inoperable, unresectable or recurrent in nature)
  • Obliterative bronchiolitis
  • Ohtahara syndrome
  • Ornithine transcarbamylase (OTC) deficiency
  • Orthochromatic leukodystrophy with pigmented glia
  • Osteogenesis imperfecta (OI) – type 2
  • Osteosarcoma, also known as bone cancer (with distant metastases or which is inoperable or unresectable in nature)
  • Ovarian cancer (with distant metastases or which is inoperable or unresectable in nature)
  • Pancreatic cancer
  • Paraneoplastic pemphigus
  • Patau syndrome (trisomy 13)
  • Pearson syndrome
  • Pelizaeus-Merzbacher disease (PMD) – connatal and classic forms
  • Peripheral nerve cancer (metastatic or recurrent)
  • Peritoneal mesothelioma
  • Peritoneal mucinous carcinomatosis
  • Perry syndrome
  • Phelan-McDermid syndrome (22q13 syndrome)
  • Pleural mesothelioma
  • Pompe disease (infantile)
  • Primary central nervous system lymphoma
  • Primary effusion lymphoma
  • Primary progressive aphasia
  • Progressive multifocal leukoencephalopathy (PML)
  • Progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome)
  • Pulmonary atresia
  • Pulmonary Kaposi’s sarcoma
  • Retinopathy of prematurity (ROP) – stage V
  • Rett (RTT) syndrome
  • Rhabdomyosarcoma (RMS)
  • Rhizomelic chondrodysplasia punctata
  • Roberts syndrome
  • Salivary cancers
  • Sandhoff disease (Sandhoff-Jatzkewitz disease)
  • Schindler disease (type 1)
  • Severe combined immunodeficiency (childhood)
  • Single ventricle heart defect
  • Sinonasal cancer
  • Small cell cancer (large intestine, prostate, uterus, lung, thymus or female genital tract)
  • Small intestine cancer (with distant metastases or which is inoperable, unresectable or recurrent in nature)
  • Smith-Lemli-Opitz syndrome
  • Spinal muscular atrophy (SMA) – types 0 and 1
  • Spinal nerve root cancer (metastatic or recurrent)
  • Spinocerebellar ataxia (SCA)
  • Stiff person syndrome (SPS)
  • Stomach cancer (with distant metastases or which is inoperable, unresectable or recurrent in nature)
  • Subacute sclerosing panencephalitis (SSPE)
  • Tabes dorsalis
  • Tay-Sachs disease (infantile type)
  • Thanatophoric dysplasia (type 1)
  • The ALS/Parkinsonism dementia complex (ALS-PDC)
  • Thyroid cancer
  • Transplant coronary artery vasculopathy
  • Tricuspid atresia
  • Ullrich congenital muscular dystrophy
  • Ureter cancer (with distant metastases or which is inoperable, unresectable or recurrent in nature)
  • Usher syndrome (type I)
  • Ventricular assist device recipient (left, right, or biventricular)
  • Walker-Warburg syndrome (WWS)
  • Wolf-Hirschhorn syndrome (WHS)
  • Wolman disease
  • Xeroderma pigmentosum (XP)
  • Zellweger syndrome (cerebrohepatorenal syndrome)

Applicants with a condition on the compassionate allowance list for Social Security disability are encouraged to mention it on their SSDI application. If you fail to inform the SSA of your condition that’s on the compassionate allowance list for Social Security disability – it’s ok. The SSA’s disability determination services agents know what disabilities to look for and may treat your application as a “dire need” claim.

You May Qualify for Legal Assistance

When applying for SSDI, many people will rely on the help of a qualified legal representative. Advocates and attorneys know the ins and outs of the program and are dedicated to helping qualified applicants get the monthly benefits they deserve. One of the best features of hiring a legal representative is that most work on a contingency basis, meaning they only get paid if you are awarded benefits.

If you’re ready to connect to a disability advocate or attorney in your area, click on the button below to take your free benefits evaluation today.

Get Your Free Benefits Evaluation